Alex French Lab

The French lab studies how psychedelics and alcohol alter the brain in order to understand how psychedelics can be repurposed into treatments for alcohol use disorder.

Alcohol use disorder

is the leading risk factor for death and disability around the world in people 15-49 years old. In the US, nearly 1 in 10 people 12 and older qualified for AUD at some point in in the past year. Alcohol misuse costs the American economy nearly $249 billion annually. Source: NIAAA

Alcohol use disorder (addiction) affects 1 in 10 people

Psychedelics

Long-referenced as trippy drugs from the '60s, psychedelics are now known to be powerful molecules that promote rewiring of neural connections in the brain. This rewiring is thought to contribute to psychedelics' success in recent clinical trials for mitigating alcohol misuse.

The Alex French Lab at the University of Wyoming researches psychedelics such as psilocybin, which is found in certain mushrooms

Signal transduction

Is a key step in how the body amplifies the effects of small molecular events - such as drug binding - into processes large enough to change a whole animal's behavior.

Signal transduction is key to understanding neurobiology and pharmacology

Our goal

Understand how the signal transduction of psychedelics can be rewired to maximize the medicinal benefit of psychedelics, without hallucinations

The Alex French Lab at the University of Wyoming researches how we can improve the pharmacology of psychedelics